Michael R Grever Selected Research

Agammaglobulinaemia Tyrosine Kinase

1/2021	Phase 2 study of ibrutinib in classic and variant hairy cell leukemia.
5/2017	BTKC481S-Mediated Resistance to Ibrutinib in Chronic Lymphocytic Leukemia.
4/2015	Etiology of Ibrutinib Therapy Discontinuation and Outcomes in Patients With Chronic Lymphocytic Leukemia.

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Michael R Grever Research Topics

Disease

56	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2023 - 06/2003
45	Neoplasms (Cancer) 01/2021 - 04/2002
16	Hairy Cell Leukemia 01/2023 - 03/2003
16	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2020 - 04/2002
16	Leukemia 02/2015 - 01/2003
7	Lymphoma (Lymphomas) 01/2019 - 12/2005
6	Tumor Lysis Syndrome 06/2016 - 03/2009
5	Infections 01/2019 - 03/2007
5	Disease Progression 09/2015 - 03/2007
5	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2014 - 09/2004
4	Lymphadenopathy 01/2023 - 01/2009
4	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 12/2020 - 04/2002
4	Multiple Myeloma 01/2019 - 11/2009
4	Neutropenia 01/2013 - 07/2010
4	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 09/2011 - 04/2007
3	Hemorrhage 07/2023 - 01/2015
3	Exanthema (Rash) 12/2022 - 03/2011
3	Breast Neoplasms (Breast Cancer) 01/2020 - 11/2009
3	B-Cell Leukemia (Leukemia, B Cell) 09/2015 - 05/2009
3	Graft vs Host Disease (Graft-Versus-Host Disease) 08/2013 - 04/2005
3	Thrombocytopenia (Thrombopenia) 01/2013 - 03/2007
3	Cytokine Release Syndrome 12/2009 - 01/2009
3	Residual Neoplasm 01/2009 - 10/2006
2	Fever (Fevers) 12/2022 - 01/2003
2	Prolymphocytic Leukemia 08/2015 - 05/2015
2	Opportunistic Infections (Opportunistic Infection) 04/2015 - 12/2005
2	Hematologic Neoplasms (Hematological Malignancy) 02/2015 - 09/2003
2	Melanoma (Melanoma, Malignant) 01/2015 - 01/2013
2	Rare Diseases (Rare Disease) 09/2014 - 02/2011
2	Nausea 01/2013 - 01/2003
2	Vomiting 01/2013 - 01/2003
2	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 09/2012 - 01/2010
2	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2010 - 10/2004
1	Lymphocytosis 01/2023
1	Pneumonia (Pneumonitis) 12/2022
1	Chromosome Aberrations (Chromosome Abnormalities) 12/2021
1	Fanconi Anemia (Fanconi's Anemia) 01/2020

Drug/Important Bio-Agent (IBA)

24	alvocidib (flavopiridol)IBA 06/2016 - 06/2005
14	fludarabineIBA 05/2015 - 01/2003
14	Pentostatin (Nipent)FDA LinkGeneric 01/2015 - 03/2003
11	Rituximab (Mabthera)FDA Link 10/2013 - 03/2003
9	ibrutinibIBA 01/2023 - 04/2015
9	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2015 - 12/2005
9	Proteins (Proteins, Gene)FDA Link 12/2014 - 07/2003
7	Decitabine FDA Link 01/2018 - 09/2007
7	silvestrolIBA 02/2015 - 05/2009
7	Cyclin-Dependent Kinases (cdk Proteins)IBA 02/2015 - 01/2007
6	Lenalidomide (CC 5013)FDA Link 12/2020 - 10/2008
6	Purine NucleosidesIBA 09/2014 - 03/2003
5	Cytarabine (Cytosar-U)FDA LinkGeneric 12/2020 - 01/2003
4	purineIBA 01/2021 - 10/2015
4	Paclitaxel (Taxol)FDA LinkGeneric 01/2020 - 06/2008
4	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 06/2014 - 06/2008
4	Bortezomib (Velcade)FDA Link 06/2014 - 05/2010
3	acalabrutinibIBA 07/2023 - 12/2020
3	VemurafenibIBA 12/2022 - 10/2015
3	Agammaglobulinaemia Tyrosine KinaseIBA 01/2021 - 04/2015
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 05/2015
3	GTI2040IBA 06/2014 - 06/2008
3	Cladribine FDA LinkGeneric 01/2014 - 10/2009
3	Adenosine DeaminaseIBA 08/2013 - 03/2003
3	DepsipeptidesIBA 02/2005 - 07/2003
3	Histone Deacetylases (Histone Deacetylase)IBA 02/2005 - 04/2002
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 03/2015
2	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 07/2014 - 09/2008
2	SteroidsIBA 08/2013 - 04/2005
2	GlucuronidesIBA 03/2013 - 03/2009
2	DNA (Deoxyribonucleic Acid)IBA 01/2013 - 07/2010
2	triphosphoric acid (triphosphate)IBA 01/2013 - 06/2009
2	Small Interfering RNA (siRNA)IBA 01/2013 - 04/2007
2	Cyclin D1IBA 01/2013 - 09/2012
2	ElectrolytesIBA 09/2011 - 01/2003
2	temsirolimus FDA Link 09/2011 - 11/2009
2	Dexamethasone (Maxidex)FDA LinkGeneric 09/2011 - 12/2009
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 09/2011 - 09/2011
2	EnzymesIBA 06/2011 - 11/2009
2	HLA Antigens (Human Leukocyte Antigens)IBA 12/2009 - 09/2003
2	Histones (Histone)IBA 03/2009 - 07/2003
2	Chlorambucil (Leukeran)FDA Link 01/2009 - 05/2006
2	Immunoglobulins (Immunoglobulin)IBA 09/2008 - 06/2005
2	Antisense OligonucleotidesIBA 06/2008 - 01/2003
2	Interleukin-2 (IL2)IBA 12/2005 - 09/2004
2	oblimersen (G3139)IBA 05/2005 - 01/2003
2	romidepsin (FK228)FDA Link 02/2005 - 07/2003
2	Histone Deacetylase InhibitorsIBA 02/2005 - 10/2004
1	venetoclaxIBA 12/2021
1	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 12/2020
1	veliparibIBA 01/2020
1	Carboplatin (JM8)FDA LinkGeneric 01/2020
1	Hormones (Hormone)IBA 01/2020
1	ImidesIBA 01/2019

Therapy/Procedure

32	Therapeutics 07/2023 - 06/2003
8	Drug Therapy (Chemotherapy) 12/2020 - 01/2003
5	Renal Dialysis (Hemodialysis) 05/2015 - 11/2007
2	Salvage Therapy 01/2023 - 04/2011
2	Drug Tapering 10/2015 - 08/2013
2	Aftercare (After-Treatment) 10/2015 - 01/2009
2	Intravenous Infusions 07/2010 - 11/2007
1	Retreatment 12/2022
1	Cell Transplantation 12/2020